Mesothelioma treatment
Treatment of malignant mesothelioma using conventional therapies has not proved successful. Treatment part is depending on many factors like stages of mesothelioma, location of mesothelioma, how far it is spread. People diagnosed with this disease are told the expected survival rate is 10-12 months.
Treatments
-Surgery
-Radiation therapy
-Chemotherapy
-Gene Therapy
-Immunotherapy
Surgery- either by itself or used in combination with pre- and post-operative adjuvant therapies, has proved disappointing. A pleurectomy is the most common surgery, in which the lining of the chest is removed in mesothelioma. Less common is an extrapleural pneumonectomy (EPP), in which the lung, lining of the inside of the chest, the hemi-diaphragm and the pericardium are removed.
Radiation therapy- radiation is often given post-operatively as a consolidative treatment. The entire hemi-thorax is treated with radiation therapy, often given simultaneously with chemotherapy. The necessary radiation dose to treat mesothelioma that has not been surgically removed would be very toxic.
Chemotherapy- Chemotherapy is defined as treatment of cancer using chemical substances .In mesothelioma cancers cells grows in the affected region. Using chemotherapy destroy the cancer cells by further multiplication. It destroys the cancer cells, to shrink the growth, and relief symptoms like pain which is very common in mesothelioma.
Gene Therapy- involves using genetic material to specifically target cancer cells and make them more vulnerable to chemotherapy treatment. When undergoing this type of gene therapy, the patient is treated with a non-infectious virus that has been altered with genetic material that makes them produce a particular protein. Following this procedure, the patient is then treated with a chemotherapeutic medication that is specially formulated to be toxic only to cancer cells. This type of therapy has produced some promising results for mesothelioma patients, but it is still only available through clinical trials.
Immunotherapy- It is a type of treatment in which the patient's own immune system is 'tricked' into killing cancer cells. There are two main types of immunotherapy: active and passive. In active immunotherapy, mesothelioma cancer cells are removed from a patient and then treated in a laboratory to turn them into a vaccine. Passive immunotherapy is somewhat different in that it does not attempt to activate the patient's immune system. Instead, it uses substances such as cytokines and other agents to help boost the patient's immune response to their cancer.